El curso pretende ser una introducción a la investigación en neurología neonatal, de tal manera que todos aquellos que realicen sus estudios de doctorado en la línea de investigación del recién nacido prematuro conozcan las particularidades de esta población.

Objetivos específicos:

• Conocer las definiciones del paciente prematuro en función de su edad gestacional y del peso. Entender cómo se calcula la edad postmenstrual.
• Entender qué factores influyen en el curso neonatal y en el pronóstico neurológico del recién nacido prematuro.
• Conocer aquellos factores que se consideran distales, intermedios y proximales.
• Entender la fisiopatología de la lesión neurológica del prematuro y su impacto en el pronóstico.
• Conocer las escalas de valoración semicualitativas de ecografía transfontanelar y resonancia magnética más usadas en la clínica.
• Aprender el manejo de algunos software para realizar segmentación manual, tanto en ecografía como en resonancia.
• Estudiar cómo es el pronóstico a largo plazo de los recién nacidos prematuros.

1. Introducción 

• El recién nacido prematuro

2. Aspectos clínicos

• Prenatales
• Perinatales
• Postnatales

3. Desarrollo cerebral, maduración y lesión neurológica en el recién nacido prematuro

4. Neuroimagen

• La ecografía transfontanelar 2D
• La ecografía transfontanelar 3D
• La resonancia magnética convencional (T1w y T2w)
• Secuencias avanzadas de resonancia magnética (Tractografía)

5. Seguimiento y pronóstico neurológico

Competencias generales:

• El alumno se familiarizará con los aspectos más importantes a tener en cuenta en el estudio del recién nacido prematuro.

Competencias específicas:

• Distinguir aquellos factores más determinantes en la evolución del recién nacido prematuro.
• Entender qué condiciona el pronóstico del recién nacido prematuro.
• Saber interpretar la ecografía cerebral y las imágenes de resonancia magnética.
• Realizar mediciones lineales, volumétricas y de los parámetros de secuencias de difusión.
• Realizar segmentación manual de estructuras de interés.

Seminarios en los que el ponente realizará una exposición con diapositivas, facilitando la interacción y la participación del alumnado

Talleres prácticos de:

• Manejo de las bases de datos disponibles.
• Segmentación en ecografía.
• Segmentación en resonancia.

Asistencia al 80% del curso.

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